women putting on oil on her face
on October 23, 2025

Retinol vs. Bakuchiol: Which One Is Better for Sensitive Skin?

If you’ve ever wanted to try retinol but worried about redness or irritation, you’re not alone. Retinol is one of the most studied and effective ingredients for anti-aging, but it’s also one of the trickiest for sensitive skin.

That’s where bakuchiol comes in, a gentler, plant-based alternative that’s become increasingly popular. But can it really deliver the same results as retinol?

What Is Retinol (and Why It’s So Effective)

Retinol is a form of Vitamin A that speeds up cell turnover and increases collagen production, two things that naturally slow down as we age.

The downside? Traditional retinol can cause dryness, flaking, and irritation, especially for those with reactive or rosacea-prone skin.

That’s why newer formulations like liposomal retinol are game changers. By encapsulating the ingredient, it’s released slowly into the skin, minimizing irritation while maintaining effectiveness.

The Age-Defying Liposomal Retinol Serum was created to bring all the benefits of retinol without the harsh side effects.

What Is Bakuchiol?

Bakuchiol is a natural extract from the Psoralea corylifolia plant. It’s often called “nature’s retinol” because it targets many of the same concerns, uneven texture, dullness, and fine lines, but without the dryness or flaking.

Unlike retinol, bakuchiol:

  • Is gentle enough for sensitive or rosacea-prone skin
  • Can be used both morning and night (it doesn’t make skin more sun-sensitive)
  • Has antioxidant and soothing properties

While it may not stimulate collagen as strongly as retinol, it’s an excellent option for those who want visible results without irritation.

Retinol vs. Bakuchiol: A Side-by-Side Comparison

Feature

Retinol

Bakuchiol

Source

Vitamin A derivative

Plant-based extract

Benefits

Boosts collagen, improves wrinkles, smooths texture

Soothes skin, reduces fine lines, improves tone

Irritation Risk

Moderate (especially for beginners)

Very low

When to Use

Night only

Morning & night

Best For

Normal to oily or aging skin

Sensitive, dry, or rosacea-prone skin


Which One Should You Choose?

If your skin can tolerate active ingredients, retinol is still the most proven option for firming and resurfacing the skin. But if you’ve struggled with redness or dryness, or you are just starting your anti-aging skincare, bakuchiol is a great alternative.

And if you want the best of both worlds? Choose an encapsulated or liposomal retinol. These advanced delivery systems, like the one used in Clinical Resolution Lab’s Age-Defying Liposomal Retinol Serum, make retinol far more tolerable for sensitive skin.

CRL Age Defying Liposomal Retinol Serum in hands White background

The Takeaway

Both retinol and bakuchiol can improve texture, tone, and fine lines. However, it’s important to choose what works best for your skin type and tolerance level.

For sensitive or redness-prone skin, bakuchiol is a gentle entry point. But if you’re ready to take your results up a notch, liposomal retinol delivers anti-aging benefits with less irritation.